Dr. Gabriel Nuñez, the Paul de Kruif Professor of Pathology, and his laboratory colleagues recently published breakthrough research results in the journal Science , describing how his team identified new key roles of the gut’s microbiota in the development of colitis.
Medulloblastomas are one of the most common types of childhood brain cancer. Thanks to Dr. Sriram Venneti, MD, PhD and his colleagues, there has been a recent breakthrough in group-3 and group-4 medulloblastomas, a tumor that appears during fetal development of the cerebellum.
A Global REACH seed grant aims to bridge stem cell biology and cutting-edge 3D retinal organoid technology to inform new research of childhood diseases that cause blindness. Rajesh C. Rao, M.D., Leonard G. Miller Professor of Ophthalmology and Visual Sciences, and Associate Professor of Human Genetics and Pathology, is a retina surgeon and physician-scientist.
Crohn’s disease (CD), one of the major forms of Inflammatory Bowel Disease, is a chronic relapsing intestinal disorder that affects millions of people globally. The cause of CD is unknown, but it is thought to result from a dysregulated immune response against environmental factors, including intestinal microbes, in genetically susceptible hosts.
The death of singer/songwriter Jimmy Buffett brought sadness to those of us who grew up listening to his music and enjoying the beach vibe. Buffett died from a rare, but aggressive, form of skin cancer called Merkel cell carcinoma (MCC). This cancer usually appears as a rapidly growing flesh colored or reddish-blue nodule on sun-exposed skin.
A study from clinicians and researchers at the University of Michigan Rogel Cancer Center, U-M Department of Pathology and the Michigan Center for Translational Pathology reveals findings from over 800 clinical assays performed for kidney patients with MiTF family gene mutations.
Congratulations to Dr. Jeffrey B. Hodgin, MD, PhD who is among the team awarded the 2023 Global Team Science Award (GTSA) given by the Lupus Research Alliance (LRA). The GTSA is given to a team of multidisciplinary researcher experts who are identifying drivers of lupus nephritis in children with the goal of improving its diagnosis and treatment.
The laboratory of Dr. Chang Kim, recently published a high-impact study that elucidates the bone marrow niche and mechanisms by which innate lymphoid cells differentiate between those which remain in the bone marrow and those which emigrate to the rest of the body.
As the SARS-CoV-2 virus continues to mutate over time and new booster vaccines become available, the question arises, are the multivalent boosters more effective at improving immune response than the monovalent vaccines with which we began? This question was addressed by a multi-site group from Columbia University Vagelos College of Physicians and Surgeons (New York) and from the University of Michigan Medical School Department of Pathology.
One of the most fascinating aspects of a career in cancer research is that one never knows when or where the next great discovery will occur. This was true of a recent breakthrough discovery made by the Dr. Russell Ryan laboratory at the University of Michigan Medical School.